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    Category: TG1050

    TG1050, an HBV-targeted immunotherapeutics, efficiently decreases HBV viremia and antigenemia in a preclinical model; a meta-analysis and the determination of the involvement of CD4 and CD8 T cells.

    Roland Kratzer, et al. AASLD & Hepatology, October 2016 – DOI: 10.1002/hep.28800 Download the poster here Poster Presentation

    Published 14 November 2016
    Categorized as 2017, Publication, TG1050 Tagged Poster presentation, Therapeutic Vaccine

    Transgene presents preclinical results of TG1050, an HBV-targeted immunotherapy, at AASLD 2016 Liver Meeting

    20161114-poster-hbv_aasld-en

    Published 14 November 2016
    Categorized as 2016, Press release, TG1050

    First Patient Randomized in Multiple Dose Cohort of Phase 1/1b Trial with Transgene’s TG1050 in Chronic Hepatitis B Patients

    20161017-tg1050-md-us-final

    Published 17 October 2016
    Categorized as 2016, Press release, TG1050

    Transgene to Continue Phase 1/1b Study with TG1050 in Chronic Hepatitis B Patients on the Recommendation of the Trial’s Safety Review Committee

    20160721 – Safety TG1050 EN Vdef

    Published 21 July 2016
    Categorized as 2016, Press release, TG1050

    Transgene Announces Dosing of First Patient with TG1050 for Treatment of Chronic Hepatitis B Infection

    20151103 TG1050 FINAL VERSION US

    Published 4 November 2015
    Categorized as 2015, Press release, TG1050

    Recognition of core-derived epitopes from a novel HBV-targeted immunotherapeutic by T-cells from patients infected by different viral genotypes.

    Ophelie Godon, et al. Vaccine. 2015 Aug 26;33(36):4548-53 – Download the article Publication

    Published 18 September 2015
    Categorized as 2015, Publication, TG1050

    TG1050, a Novel Immunotherapeutic to Treat Chronic Hepatitis B, can Control HBsAg and Provoke HBsAg Seroconversion in HBV-Persistent Mouse Models

    Karine Lélu, et al. EASL Liver Congress 2015, Vienna-23th April 2015 Download the poster here Poster Presentation

    Published 30 April 2015
    Categorized as 2015, Publication, TG1050

    Transgene Presents New Data with TG1050, an Immunotherapy being Developed to Treat Chronic Hepatitis B, at The International Liver Congress™ 2015

    20150423 – US – EASL2015 TG1050

    Published 23 April 2015
    Categorized as 2015, Press release, TG1050

    Viral hepatitis: HBV cure—can we pin our hopes on immunotherapy ?

    Hung-Chih Yang, et al. Nature Reviews Gastroenterology & Hepatology (2015) doi:10.1038/nrgastro.2015.8 – Download the article Publication

    Published 5 February 2015
    Categorized as 2015, Publication, TG1050

    TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice.

    Martin P, Dubois, et al. Gut. 2014 Nov 26, doi: 10.1136/gutjnl-2014-308041 – Download the article Publication

    Published 26 November 2014
    Categorized as 2014, Publication, TG1050

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