Transgene – L'immunothérapie contre les cancers

Phase I trials of personalized cancer vaccine TG4050 in surgically treated high-risk head and neck squamous cell carcinoma (HNSCC) and relapsing ovarian cancer (OvC) patients

MS Block et al. AACR 2022 Download the publication here

Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject “cold” tumors

Semmrich M, Marchand J, Fend L, et alJournal for ImmunoTherapy of Cancer Download the publication herePoster Presentation

Bioavailability and activity of oncolytic virus TG6002 after intravenous administration in patients with advanced gastrointestinal carcinomas

P. Cassier et al. ESMO 2021 Download the poster here Poster Presentation

BT-001, an oncolytic vaccinia virus armed with a Treg-depleting human recombinant anti-CTLA4 antibody and GM-CSF to target the tumor microenvironment

Poster BT-001 M. Semmrich et al. SITC 2020 Download the poster here Poster Presentation

TG4001 (Tipapkinogene sovacivec) and avelumab for recurrent/metastatic (R/M) Human Papilloma Virus (HPV)-16+ cancers: clinical efficacy and immunogenicity

Poster SITC TG4001 C. Le Tourneau et al. SITC 2020 Download the poster here Poster Presentation

Performance of neoantigen prediction for the design of TG4050, a patient specific neoantigen cancer vaccine

AACR2020 myvac B. Mallone et al. AACR 2020 Download the poster here Poster Presentation

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